Protective Effect of Ketamine against Acetic Acid-Induced Ulcerative Colitis in Rats
نویسندگان
چکیده
منابع مشابه
Protective effect of Mumiju against acetic acid-induced ulcerative colitis in rats
Objective: In this study, we elucidated the ameliorative effect of aqueous extract of leaves of Mumiju against acetic acid-induced experimental colitis in male rats. Materials and Methods: The animals were randomly divided into four groups (n=7) including I: control group, II: vehicle group (injected with 2 ml acetic acid (4%) intra rectally), III and IV: treatment groups which received Mumiju ...
متن کاملProtective Effect of Ketamine against Acetic Acid-Induced Ulcerative Colitis in Rats
Objective: Inflammatory bowel diseases (IBD), including Crohn’s disease and ulcerative colitis (UC), are chronic and recurrent disorders of the gastrointestinal tract with unknown etiology. Considering the adverse effects and incomplete efficacy of currently administered drugs, it is crucial to explore new drugs with more desirable therapeutic profiles. As non-competitive N-methylD-aspartate (N...
متن کاملThe Effect of Grape Seed Oil Enema with or without Sesame Oil in Acetic Acid Induced Ulcerative Colitis of Rats
BACKGROUND Inflammatory bowel diseases contain two digestive system diseases, ulcerative colitis (UC) and Crohn’s disease with unclear causes. The aim of present study was to investigate the therapeutic effects of administration of the Sesame oil (SO) and grape seed oil (GSO) as enema route in rats suffering from experimental acetic acid induced UC. METHODS Eighty male rats were ...
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Background & Objective: Ulcerative colitis is one of the common causes of gastrointestinal tract diseases in developing countries. This disease causes disability, especially in young adults, and imposes many social and economic burdens on the community. The aim of this study was to investigate the effects Effect of Fasciola hepatica extract on acetic acid induced ulcerative colitis in rat model...
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Background: Ulcerative colitis is an idiopathic chronic, relapsing inflammation of the colon which is resulted from dysregulation of the mucosal immune system. In Iranian traditional medicine, oleoresin from Pistacia atlantica is used to treat gastrointestinal disorders, including peptic ulcers, dyspepsia and intestinal inflammation. Objective: In this study, we examined the therapeutic and pro...
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ژورنال
عنوان ژورنال: Pharmacology & Pharmacy
سال: 2016
ISSN: 2157-9423,2157-9431
DOI: 10.4236/pp.2016.71002